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Dr. Lisa Bornewasser


Universität zu Köln
Department für Chemie
Greinstaße 4
50939 Köln

Raum: 415

Telefon:+49 221 470 76062

E-Mail: lisa.bornewasserSpamProtectionuni-koeln.de

Academic Background

2018/09 – 2023/03     PhD/Dr. rer. nat. in Biochemistry, Kath-Schorr lab,
                                       University of Cologne, former University of Bonn, DE
                                       PhD thesis: “Developing new methods for specific RNA modification

 

2015/10 – 2017/09      M.Sc. Chemistry, University of Bonn, DE
                                        Master thesis: “Preparation of cyclopropene labelled mRNAs via genetic
                                        alphabet expansion transcription
” (Kath-Schorr lab)

 

2012/10 – 2015/09     B.Sc. Chemistry, University of Bonn, DE
                                       Bachelor thesis: “Experiments on spin labelling the ferrous iron transporter
                                       FeoB from Escherichia Coli by use of unnatural amino acids
” (Schiemann lab)

Awards

2022/06                       Poster prize, Biochemistry 2022 Conference, Münster, DE

Publications

Stronger Together for in Cell Translation: Natural and Unnatural Base Modified mRNA
L. Bornewasser, C. Domnick, S. Kath-Schorr, Chem. Sci. 2022, 13, 4753‑4761.
DOI: 10.1039/D2SC00670G

Preparations of Site-Specifically Spin-Labeled RNA by In Vitro Transcription Using an Expanded Genetic Alphabet
L. Bornewasser, S. Kath-Schorr, Methods Mol. Biol. 2022, 2439, 223‑240.
DOI: 10.1007/978-1-0716-2047-2_15

Strategies for Covalent Labeling of Long RNAs
H. Depmeier, E. Hoffmann, L. Bornewasser, S. Kath-Schorr, ChemBioChem 2021, 22, 2826‑2847
DOI: 10.1002/cbic.202100161

EPR Distance Measurements on Long Non-Coding RNAs Empowered by Genetic Alphabet Expansion Transcription
C. Domnick, F. Eggert, C. Wuebben, L. Bornewasser, G. Hagelueken, O. Schiemann, S. Kath-Schorr, Angew. Chem. Int. Ed. 2020, 59, 7891‑7896.
DOI: 10.1002/anie.201916447

Studies on the X-Ray and Solution Structure of FeoB from Escherichia Coli BL21
G. Hagelueken, J. Hoffmann, E. Schubert, F. G. Duthie, N. Florin, L. Konrad, D. Imhof, E. Behrmann, N. Morgner, O. Schiemann, Biophysical Journal 2016, 110, 2642‑2650.
DOI: 10.1016/j.bpj.2016.05.018

Conferences

Biochemistry 2022, Münster, DE

Novo Nordisk Chemist of the Future Symposium 2022, Favrholm, DK

IX. Nukleinsäurechemietreffen 2019, Saarbrücken, DE

Advance in Chemical Biology 2019, Frankfurt, DE

RNA Biochemistry 2018, Bonn, DE